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Friday, January 20, 2012
U.S. Strategic Command Mysteriously Deletes Russian Mars Spacecraft's Tracking Data After Sabotage Accusations [Space]
Hospital chief testifies about Brooks' donation
Garth Brooks rubs his brow while talking to reporters after a day of testimony in a breach-of-promise trial at the Rogers County Courthouse in Claremore, Okla., on Thursday, Jan. 19, 2012. Brooks is suing the Integris Canadian Valley Regional Hospital, saying it wouldn't name a women's center for Colleen Brooks after receiving $500,000 from him. (AP Photo/Tulsa World, Matt Barnad) TV OUT; TULSA OUT
Garth Brooks rubs his brow while talking to reporters after a day of testimony in a breach-of-promise trial at the Rogers County Courthouse in Claremore, Okla., on Thursday, Jan. 19, 2012. Brooks is suing the Integris Canadian Valley Regional Hospital, saying it wouldn't name a women's center for Colleen Brooks after receiving $500,000 from him. (AP Photo/Tulsa World, Matt Barnad) TV OUT; TULSA OUT
Garth Brooks talks to reporters while his wife Trisha Yearwood, right, looks on after a day of testimony in a breach-of-promise trial at the Rogers County Courthouse in Claremore, Okla., on Thursday, Jan. 19, 2012. Brooks is suing the Integris Canadian Valley Regional Hospital, saying it wouldn't name a women's center for Colleen Brooks after receiving $500,000 from him. (AP Photo/Tulsa World, Matt Barnad) TV OUT; TULSA OUT
Garth Brooks and attorney John Hickey, right, leave the Rogers County Courthouse after a day of testimony in a breach-of-promise trial in Claremore, Okla., on Thursday, Jan. 19, 2012. Brooks is suing the Integris Canadian Valley Regional Hospital, saying it wouldn't name a women's center for Colleen Brooks after receiving $500,000 from him. (AP Photo/Tulsa World, Matt Barnad) TV OUT; TULSA OUT
CLAREMORE, Oklahoma (AP) ? A hospital executive discussed country singer Garth Brooks' request that the facility return a $500,000 donation in an email to staff members in March 2009, according to trial testimony Thursday.
Brooks wants the Integris Canadian Valley Regional Hospital in his hometown of Yukon to return the money, claiming in a lawsuit that hospital administrators reneged on their pledge to name a part of a medical complex after Colleen Brooks.
The Tulsa World (HYPERLINK "http://bit.ly/Avdi1z" ) reports that the hospital president's March 2009 email about Brooks' request for the money back was discussed during testimony Thursday. The email from CEO and President James Moore stated the hospital "may not deny Garth access to the money," but could "make him work to get it."
Moore on Thursday reiterated his earlier testimony that he never made an agreement with Brooks on naming rights in connection with the $500,000. He said the gift from Brooks was anonymous and "unrestricted," meaning Integris could use the money at its discretion.
Defense attorney Terry Thomas showed jurors a September 2008 email from Brooks to Moore. In it, Brooks said, "... I'm not sure what our understanding is," but "... we have to come to some agreement ..."
Earlier, Moore testified that Brooks considered donating up to $15 million if the facility would rename itself after his mother. An internal document from the hospital quotes Brooks as saying a $15 million gift for naming rights was "exactly" what he had in mind.
Colleen Brooks died of cancer in 1999. A women's center never was built.
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Thursday, January 19, 2012
Exclusive: Astro Signs With 'X Factor' Mentor L.A. Reid
Teenage MC will be on today's 'RapFix Live' at 4 p.m. on MTV.com to discuss his new deal with Epic Records.
By Rob Markman
Astro
Photo: Getty Images
Astro might not have taken home top honors on "X Factor," but the 15-year-old Brooklyn MC scored a huge win nonetheless. MTV News has exclusively learned that the Astronomical Kid signed a deal with "X Factor" mentor L.A. Reid over at Epic Records. The young rap phenom will appear on today's "RapFix Live" to formally announce the deal in detail.
After the teenage rapper was sent home during the show's December 1 episode, rumors began to swirl about where he would end up. Reports that 'Stro would sign with Jay-Z's Roc Nation hit the Web early, but in an interview with MTV News, the pint-size MC quickly shot that notion down.
"I have never met anyone from Roc Nation. I'd love to, but I'm not signed right now to anyone," he said during a December 5 interview. "Nobody ever hit me up about that — just go on the Internet and it's up there. But I'm not signed, as far as I know."
Though Hov is one of his favorite rappers, the Brooklyn whiz kid wasn't necessarily looking to sign based off star power alone. "I just want to be in a place where I'm comfortable 100 percent. I just want to be able to release my music, do my movies, [and] everything is fair," he told MTV News of his dream deal. "I just want to be able to have fun doing it. I don't want music to be a job for me; I want it to be something I'm doing for fun. As long it's not a job, then you're straight."
It seems that Reid has provided the youngster with everything he was looking for. No word yet on when Astro will drop his debut album, but then again, at 15 years old, he has all the time in the world.
What do you think of Astro's deal with Epic Records? Tell us in the comments!
Catch Astro, Naughty by Nature and Khalil Kain on "RapFix Live" today at 4 p.m. ET on MTV.com, and be sure to join the Twitter conversation using the hashtag #RapFixLive. Send your questions for the artists @MTVRapFiX!
Source: http://www.mtv.com/news/articles/1677442/astro-record-deal-epic.jhtml
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Roche melanoma pill spurs growth of less harmful cancers (Reuters)
CHICAGO (Reuters) ? A new study helps explain why up to a third of advanced melanoma patients who take Roche Holding's pill Zelboraf develop a less deadly form of skin cancer known as cutaneous squamous cell carcinoma, and even points to a potential fix.
They said combining drugs like Zelboraf, which block a mutation known as BRAF, with a second melanoma drug that blocks a different mutation known as MEK helped to solve this problem in lab mice.
GlaxoSmithKline has already shown early promise in a trial combining drugs that block both MEK and BRAF, and the study shows why this duo may be more effective and have fewer side effects than drugs that target either mutation separately.
Both MEK and BRAF are mutations in the same pathway are used by the cancer to drive tumor growth.
"The combination of BRAF and the MEK inhibitors gives you a better response, and also prevents the emergence of these secondary tumors," said Professor Richard Marais of the Institute of Cancer Research in London, whose study appears in the New England Journal of Medicine.
About 50 percent of patients who get melanoma have the BRAF mutation and can be treated with vemurafenib. But doctors noticed that many of these patients developed another type of skin cancer called cutaneous squamous cell carcinoma, which had to be removed surgically.
To understand why, the team -- which included researchers from the University of California Los Angeles, Roche and Daiichi Sankyo's Plexxikon -- studied squamous cell cancer tissue from 21 malignant melanoma patients who had been treated with vemurafenib in a clinical trial.
They found about 60 percent also had RAS mutations, likely caused by sun exposure, that could predispose them to squamous cell cancer. And unlike melanoma cells, when these mutated cells became exposed to a BRAF inhibitor, they tend to grow.
"It's not that these drugs (BRAF inhibitors) are tumor promoters. What they do is accelerate growth of preexisting but asymptomatic tumors in the skin of patients who are susceptible to that disease," he said.
Treatment with a MEK inhibitor blocks this side effect, Marais said.
Tests in lab mice found that those with both types of skin cancers who were treated with a combination of a BRAF and MEK drug had fewer lesions.
And there are hints that process may work in people.
In June, GSK presented the first data from its combination BRAF and MEK inhibitors at the American Society of Clinical Oncology meeting in June.
"One of the things they found is the patients had fewer skin lesions. It actually works in people," Marias said.
He said the findings may spur more companies to combine their BRAF and MEK inhibitors.
"Not only will it give you the best response but it won't give you the secondary events," he said.
Melanoma globally afflicts nearly 160,000 new people each year. It can spread quickly to internal organs and average survival is six to nine months.
Zelboraf was developed in partnership with Daiichi Sankyo and is the second drug to be approved for melanoma in recent months. Prior to 2011, the FDA had not approved a new melanoma drug in 13 years.
(Reporting By Julie Steenhuysen; Editing by Eric Walsh)
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Wednesday, January 18, 2012
DinoMarket.com : Native Union Retro Handset - Pop Phone - Desert
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Source: http://www.dinomarket.com/TokoDino/110746/Native-Union-Retro-Handset-Pop-Phone-Desert/
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